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Active and latent forms of transforming growth factor beta activity in synovial effusions
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The Metsera acquisition suggests Pfizer believes metabolic disease is a priority area to become a top-tier business we should watch Pfizers pipeline for new obesity/metabolism projects (possibly built via smaller partnerships)
the published research on the LR3 analog specifically is primarily in (a) mechanistic and pharmacokinetic studies in animals and isolated tissues, (b) cell culture applications (it is widely used as a serum-free supplement for stem cell and cell-line maintenance), and (c) analytical/anti-doping methodology (LR3 is on the World Anti-Doping Agency prohibited list)
Research on this topic is still ongoing, however, and it may take time to determine the long-term effects of these drugs
It can be used in many types of formulations as it has great thermal stability (can be heated up to 85C) and works on a wide range of pH levels (ph 3-10)
