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J Am Coll Cardiol 2019;73:2049-58

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Among the GSH peroxidase family, GPX4 is uniquely critical in ferroptosis, acting as a key negative regulator by directly reducing lipid peroxides to suppress cell death (22)

This section explains the common and serious side effects of each drug, how they compare, and what patients should discuss with their healthcare provider before starting treatment

Therefore, enhancing intracellular glutathione represents one of the most promising strategies to restore redox balance, strengthen cellular integrity, and delay aging

Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, Lindholm C, Snowden J, Adamson J, Sadovnick AD, Rollinson S, et al