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On funnel plot analysis, the studies occupied symmetrical distribution based on weight and converged toward the pooled effect as the weight increased, so there was no evidence of publication bias (Fig

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Clothes that fit snugly at baseline now hang loosely, though most people have not yet needed to replace their entire wardrobe

Because any apnea benefit comes from losing weight rather than a direct airway effect, the important question with any of these medications is the same: is your AHI actually changing

Most research on these substances remains preclinical: cell studies and animal models, with very limited human data

Any decision about this medication belongs with a licensed prescriber