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Mass spectrometry Whole-cell proteome (WCP) was performed in HeLa Flp in T-Rex TM RNF4 WT cells, pre-treated with doxycycline (1 g/ml) for induction of RNF4 expression for 24 h before addition of PROTACs with a final concentration of 5 M

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Storage and Administration Both compounds are administered as subcutaneous injections, typically in the abdomen, thigh, or upper arm

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