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Although the association is not proven in human studies, patients with medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 must avoid Mounjaro

Ongoing inflammatory conditions can affect B12 status

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Not a footnote in a broader chart

Weight & metabolic improvement GLP-1 medications (semaglutide or tirzepatide) produce clinically meaningful weight loss while also improving blood pressure, cholesterol, metabolic inflammation, and glycemic control

For oral semaglutide (Rybelsus), the absorption problem runs in the opposite direction as well: the drug itself requires a fasting stomach and an empty small intestine