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Symptoms of anaphylaxis include swelling of the face, lips, and neck along with rapid heartbeat, and trouble breathing
The consequent impairment in oxalate homeostasis can trigger localized and systemic inflammation, progressive kidney disease and cardiovascular complications, including sudden cardiac death
A more recent hypothesis postulates that high-dose folic acid redirects the active form of vitamin B12 in serum, i.e., holotranscobalamin, either toward the bone marrow to support reticulocyte synthesis that is induced by folic acid in B12-deficient patients, or into the urine in which it is excreted instead of being taken up and recycled into circulation through the kidneys (84)
Nothing is prescribed without a proper clinical evaluation
Patients with blood disorders often exhibit lower serum concentrations of 25(OH)D3, the precursor to calcitriol (1,25(OH) 2 D3, active form of vitamin D), compared to healthy individuals
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