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For people with MTHFR mutations, synthetic folic acid can actually block folate receptors and worsen symptoms

While it has been established that tirzepatide leads to more weight loss than semaglutide in patients with type 2 diabetes, researchers noted that more information is still needed about how they compare in general obese/overweight patient populations

The traditional measure of scale weight gain becomes less relevant when the objective shifts toward lean tissue accumulation with minimal fat storage

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