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RosenstockJPerkovicVJohansenOECooperMEKahnSEMarxNet al

Baseline measurements before starting, periodic monitoring during use, and follow-up assessment after cycling off provide data points that can reveal individual response patterns

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These prespecified analyses considered factors such as age, hypertension, heart failure, eGFR, proteinuria, new users after the index day, enrollee after 2006 and concurrent usage of other medications for glycemic control, and renin-angiotensin-aldosterone system (RAAS) blockers

It does this without increasing cortisol or prolactin levels or causing hunger, as can happen with growth hormone receptors