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doi: 10.2147/HIV.S430310 40

This analysis showed that semaglutide (both oral and sc) reduces the continuum relative and the absolute risk of MACE, especially in medium to high-risk patients, with no difference between trials evaluating only blood glucose control or cardiovascular events, and also with studies without active comparator, only versus placebo

Moreover, iron-activated microglia can engage in the aberrant elimination of viable neurons and synapses, further contributing to ferroptosis-induced neurodegeneration

Taken together, our study demonstrated that ferroptosis played an important role in AKI induced by FA overdose injection in mice, which could be alleviated by LA supplementation, indicating that LA may be used as a potential therapeutic approach to ameliorate AKI caused by drugs or toxicants in the clinic