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Similar patterns appeared in other obesity-related cancers: Non-small cell lung cancer: progression to Stage IV roughly 10% versus 22% Colorectal cancer: statistically significant reduction in progression Hepatocellular (liver) cancer: signal in the same direction A separate JAMA Oncology study by Dai and colleagues (2025), distinct from the Cleveland Clinic ASCO analysis, found about a 17% lower overall cancer incidence (hazard ratio approximately 0.83) in adults with obesity who used GLP-1 receptor agonists, with most of the signal coming from skin cancers and obesity-related solid tumors
Conclusion GLP-1 stands out as a promising avenue in the pursuit of weight loss
doi: 10.1016/S0022-2275(20)41151-4 61 GalsgaardKDPedersenJKnopFKHolstJJWewer AlbrechtsenNJ
2021 Aug 16;13(8)
Neurobiol Learn Mem (2010) 93(4):54653
Chemotherapy drugs may have altered effectiveness, as antioxidant properties could interfere with treatment mechanisms
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