Semaglutide : Known for its prolonged action, semaglutide offers sustained appetite suppression and blood sugar control
In a phase II study of the long-acting GLP-1RA efpeglenatide (4 mg once weekly, 6 mg once weekly, 6 mg once every 2 weeks, and 8 mg once every 2 weeks), patients with obesity and without diabetes had statistically significant reductions in body weight compared with placebo after 20 weeks of treatment (differences in least squares means were 6.3 to 7.2 kg
This makes it a reliable backup when abdominal fat decreases during your weight loss journey
Patients should never discontinue or adjust medications without provider guidance, as abrupt changes can lead to worsening or uncontrolled blood pressure or loss of glycemic control
That follow-up trial, involving 536 obese adults over 24 weeks, failed to meet its primary efficacy endpoint, meaning the fat-loss effect seen at the smaller scale did not hold up in the pivotal study
Fresh ginger tea (steep sliced fresh ginger in hot water for 10 minutes), ginger capsules, or even candied ginger can all help