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The contribution of these metabolites was only detectable when cells were cultured under physiological conditions

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Interestingly, Deferoxamine (DFO), Fer-1, and GSH can reduce the cytotoxic effects of Saikosaponin A, while Z-VAD-FMK is ineffective in preventing Saikosaponin A-induced cell death in HCC (96)

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Phenobarbital (Luminal) High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital