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By addressing the biological hurdles to weight loss, Zepbound makes creating a calorie deficit more manageable without persistent hunger

He said: "These are the most powerful glucose-lowering drugs on the planetthey are more effective at getting the average glucose lower than even insulin, in the setting of Type 2 diabetes

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These behavioral changes, combined with consistent physical activity (150+ minutes per week of moderate exercise), create a metabolic foundation that persists even after the medication ends