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Serious but rare adverse events include pancreatitis, gallbladder disease, and hypoglycaemia (particularly in patients taking concomitant diabetes medications)
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Hence, although tumor-reactive T cells are numerically insufficient and functionally debilitated in the TME, strategically modulating preexisting functionally competent bystander T cells may offer a previously underappreciated avenue for overcoming the current limitations of cancer immunotherapy in the future
Commenting on the study, Sheona Scales, Director of Research, Alzheimers Research UK, said: Research shows that nearly half (45%) of dementia cases are linked to 14 risk factors, including type 2 diabetes
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