T cell activation by APCs induces symptoms similar to those in patients with IBD 37
refer to the MHRA/EMC SmPC and NHS medicines information for full details
But pharmacovigilance databases tell a different story, one where 144 cases of anxiety have been reported among GLP-1 receptor agonist users
Semaglutide (sold under the trade names Wegovy and Ozempic) is a medication designed to mirror the effects of GLP-1, a hormone created and released in the gut as a response to eating
Abbreviations ADA: American Diabetes Association CV: Cardiovascular CVOTs: Cardiovascular outcome trials GLP-1RA: Glucagon-like peptide-1 receptor agonists HR: Hazard ratios MACE: Major cardiovascular events SGLT-2i: Sodiumglucose transporter-2 inhibitors T2DM: Type 2 diabetes mellitus References Giugliano D, Maiorino MI, Longo M, Bellastella G, Chiodini P, Esposito K
Similar to tirzepatide, dulaglutide stimulates insulin secretion, inhibits glucagon release and promotes satiety