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If you have pernicious anaemia, you are about three times more likely to develop stomach cancer than someone without pernicious anaemia, even when the anaemia is treated

This group also includes newer indication-specific treatments such as elamipretide, which received accelerated FDA approval in 2025 to improve muscle strength in adults and children with Barth syndrome

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Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress