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Unlike medications such as Ozempic or Wegovy that target one or two receptors, Retatrutide activates three different hormone pathways in your body

14 Its impact extends beyond the hypothalamus, possibly including the brain stem

As patients lose weight, they often experience increased energy levels and reduced fatigue, making it easier to engage in physical activities and maintain a healthy lifestyle

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Reducing visceral fat

Other secondary endpoints also favored tirzepatide: longer 6-minute walk distance, greater change in body weight (-11.6%), and lower high-sensitivity C-reactive protein levels and systolic blood pressure (-4.7 mm Hg)