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Therapeutic approaches include the inhibition of FAO, ROS detoxification pathways, and autophagy

Additionally, the expression levels of C1q , C4 , C1s , C2 , C3 , C5 , C7 , CFD , C3AR1 , C4A , (72) and C5AR1 are significantly upregulated on day 7 post-interaction

doi: 10.1016/j.cmet.2019.11.021 152 KenisonJEJhaveriALiZKhadseNTjonETezzaSet al

Importantly, no serious safety concerns have emerged from available clinical data, though long-term safety studies spanning multiple years remain limited