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Graphical abstract Pediatric obesity is associated with insulin resistance, chronic inflammation, and psychosocial consequences

KEY QUOTE The current state of access to weight loss drugs isnt serving everyone who needs them, said Andrew Dudum, CEO and co-founder of Hims & Hers

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Semaglutide and Wegovy also offer prolonged effects, with half-lives that support weekly administration

Genetic predispositions do not determine therapy success but inform dose expectations, side effect likelihood, and timing of dose escalation

The medication also helps strengthens the body and increases sperm concentration, assisting in maintaining an active lifestyle