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Description

Sirtuin-1 can promote Nrf2 deacetylation and enhance its transcriptional activity, further protecting against mitochondrial oxidative stress (Xu et al., 2021)

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Patients initially received intramuscular acetyl-l-carnitine at a dose of 500 mg twice daily for an average of 57 9 days, followed by oral administration at the same dose for up to 6 months

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