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Cardiovascular benefits, including reduced heart attack and stroke risk, have been documented in people with existing heart disease, making semaglutide not just a weight-loss tool but potentially a medication that protects your heart

It names severe renal impairment, specified as an eGFR below 30 mL/min/1.73m2, as a contraindication to semaglutide-metformin therapy

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Step 4: dissolve gently Do not shake the vial

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