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Using PSM on age at index, BMI, metformin and statin exposure, BRCA mutation status, hormonal contraceptive use, parity, breastfeeding history, and smoking status, they identified 2 balanced cohorts: 74,354 GLP-1 RAexposed women and 74,355 controls (total n = 148,709)

In rats, feeding activity and food intake decreased following intracerebroventricular injection of GLP-1, an effect counteracted by co-administration of a GLP-1 receptor antagonist (71, 72), suggesting central GLP-1 as a potent inhibitor of feeding

Ferroptosis, a form of regulated cell death initiated by lipid peroxidation, differs from other types of cell deaths at genetic, biochemical, and morphological levels 24,25

European Teratology Information Services Study (BMJ 2024) Design: Prospective observational cohort Sample: 168 GLP-1 RA-exposed pregnancies, compared with diabetic and obese reference groups Findings: Major birth defect rates: 2.6% (GLP-1 RA) vs

An early appointment reduces the length of fasting required, helping maintain stable blood sugar levels

Vitamin B12 is an essential nutrient that many people dont get enough of in their diets