Its harder, and we dont have all the hormones on board, and we dont have as marked muscle protein synthesis as we did when we were young
GLP-1 medications can alter the absorption and effectiveness of oral medications, including oral contraception(birth control) and oral hormone replacement therapy (HRT)
Furthermore, a prespecified subgroup analysis of HF individuals from the SELECT trial evaluating the effects of semaglutide on cardiovascular outcomes in people with overweight or obesity, which included 2,273 HFpEF and 1,347 HFrEF patients, showed that the therapy was associated with a reduction in the HF composite outcome (cardiovascular death or HF hospitalisation/emergency visit) across LVEF, suggesting that GLP-1 RAs may improve outcomes at least in obese HF patients regardless of diabetes status
One of the first studies to demonstrate the potential of GLP-1 drugs to curb alcohol addiction was published in 2022
Studies have found benefits with beta-glucan at doses ranging from 3 to 15 grams daily for improving total and LDL cholesterol, with the most reliable benefits seen at higher doses 18
In very rare cases, a more systemic allergic reaction can develop, presenting as hives or difficulty swallowing
