Prescription rate of GLP-1s based on diagnosis Source: Piaopiao, L et al JAMA Network Open October 31, 2025 Research published in JAMA Network Open evaluated trends in prescribing of GLP-1 agents from 2010 through the end of 2024 using the Cosmos data warehouse, which has at least some medical records for 300 million Americans
It plays a role in how our brain processes rewards, which is closely tied to our mood and motivation
However, clinical trials have shown that individuals may lose weight and experience improved blood glucose levels on both drugs
A generic entry may be possible by 2026 if legal challenges succeed or patents expire earlier
Mounjaro is branded, pre-filled pens with higher cost
When these factors are addressed, muscle pain resolves without lasting effects