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That selectivity is one reason SSRIs are often used as first-line treatments for anxiety and depression, especially when both are present

What to track Symptoms log: Hot flash frequency and severity Sleep quality (hours, quality 1-10) Energy levels daily Mood and anxiety Brain fog incidents Period timing (if still menstruating) Body composition: Weight weekly (understanding fluctuations normal) Body measurements (waist, hips) Photos every 2-4 weeks How clothes fit Muscle vs fat changes Hormone-related: Menstrual cycle length and flow PMS symptoms Breast tenderness Libido changes Vaginal dryness Quality of life: Exercise performance Work productivity Relationship satisfaction Social engagement Overall well-being Bloodwork for perimenopause peptides Baseline testing: Estradiol (estrogen) Progesterone Testosterone (total and free) FSH (follicle-stimulating hormone - elevated in perimenopause) Thyroid panel (TSH, Free T3, Free T4) IGF-1 (growth hormone marker) Fasting glucose and insulin Lipid panel Follow-up (every 3-6 months): IGF-1 (should increase with GH peptides) Thyroid panel Fasting glucose Hormones if on HRT Adjusting based on results: Low IGF-1 still

Lifestyle Tips Avoid fizzy drinks and excess alcohol

Mikki) offers this powerful combination as part of comprehensive anti-aging and wellness programs

Knowing this pattern allows you to plan meals and social eating events around periods when you feel less hungry, making it easier to stick to your nutrition goals without fighting intense cravings

Other potential interactions While rare, Semaglutide can interact with some medications that affect kidney function or blood pressure