7.2 Natural polyphenols and alkaloids As an antioxidant polyphenolic compound and a free radical scavenger, resveratrol has attracted interest for the potential treatment of thyroid diseases accompanied by increased ROS production, such as autoimmune thyroiditis and hyperthyroidism ( In vitro and in vivo studies have also demonstrated that resveratrol mediates the levels of TSH and iodide uptake in thyrocytes by decreasing NIS expression ( Alkaloid antioxidant berberine was recently reported to exert positive effects in treating GD
FDA therefore identified a theoretical carcinogenic concern where chronic exposure activates telomerase or extends telomeres in cells capable of malignant transformation
For preclinical tissue models, stronger evidence would require standardized injury models, blinded outcome assessment, histological confirmation, functional endpoints, and comparison against appropriate positive and negative controls
And theyre documented, not fluff, not hype
Neuron 77 , 1934 (2013)
Symptoms may include a rash, difficulty breathing, and more