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4, Table 5 in the Appendix)

10.1210/jc.2005-2220 77 LiuJ.ZhuD

Nevertheless, the fact that DPP-4 is a key player in the clearance of both endogenous peptides has been exploited pharmacologically and, as mentioned above, DPP-4 inhibitors are now an established therapy of T2DM

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The analysis included 10,997 adults with CM initiating a GLP-1 RA (liraglutide, semaglutide, dulaglutide, exenatide, lixisenatide, or albiglutide) within 12 months of diagnosis, as well as matched adults initiating topiramate.The researchers found that compared with topiramate, GLP-1 RA initiators had a lower risk for emergency department visits (risk ratio [RR], 0.90), hospitalizations (RR, 0.86), nerve blocks (RR, 0.87), and triptan use (RR, 0.87)