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Supporting these findings, reduced maternal and placental CoQ10 levels have been reported in women with severe PE, further implicating mitochondrial dysfunction and OS in disease severity 42

Valproate overdose leading to hyperammonaemic encephalopathy

The Endocrine Society's 2023 clinical practice guideline on obesity pharmacotherapy identifies hepatic fat as a secondary treatment target that justifies continued therapy independent of weight-loss response [15]

Cork, PhD , study co-author, physiologist, and senior lecturer in the School of Medicine at Anglia Ruskin University

Emerging data suggests multi-agonist compounds may result in a different lean mass profile compared to GLP-1only peptides, although research is ongoing

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