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Imagine if the mortality benefit of semaglutide continues to expand over 10 years and we can deliver this intervention at scale
GLP-1s are not for everyone
OHB protective pathways in Aralar-KO neurons and brain: an alternative to ketogenic diet
Even when insulin is used, these classes of medications still provide benefits. Joanna Khatib In a meta-analysis, Khatib and colleagues assessed major adverse CV events from eight recent CV outcome trials for SGLT2 inhibitors, GLP-1 receptor agonists and DPP-IV inhibitors: DECLARE, EMPA-REG, EXSCEL, HARMONY, LEADER, SUSTAIN-6, EXAMINE and SAVOR-TIMI 53
Science 356 , eaam7263 (2017)
The most common side effects are gastrointestinal, including nausea (affecting 20-40% of patients), vomiting, diarrhoea, constipation, and abdominal discomfort
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