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Diabetes 62 , 30443052 (2013)

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Another study also carried out in HEK-293 cells showed that incretin heterodimers can form constitutively and that stimulation of GLP-1R with GLP-1 promotes incretin heterodimerisation whereas GIP stimulation reduces it ( q and -arrestin recruitment to the GLP-1R whereas GLP-1 stimulation enhances recruitment of G s to the GIPR

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