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The weight-loss medications semaglutide (Wegovy) and tirzepatide (Zepbound) have been game changers for millions of Americans who want to shed extra pounds

Selenium: This mineral is a cofactor for the enzyme that allows glutathione to neutralize free radicals

It is the single most important factor separating tirzepatide from retatrutide

Retatrutide side effects appear to be dose-related, with higher doses generally linked to more frequent or noticeable symptoms

The body requires a continuous energy supply, but when food is unavailable, it lowers insulin levels and releases another hormone, glucagon

Results A summary of the review findings can be found in Table 1 (Supplemental File 2)