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Issues like cost, availability, side effects (such as nausea), and the simple fact that obesity is a complex condition drive the search for other solutions

doi: 10.3748/wjg.v29.i14.2078 251 HaghighatNRajabiSMohammadshahiM

Adding cagrilintide, which has its own GI effects, to an aggressively-dosed retatrutide protocol without careful titration is a recipe for poor tolerance and treatment discontinuation

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