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Without sufficient B12, this sheath can weaken, which may explain symptoms such as tingling, numbness, memory issues, or brain fog. From an energy standpoint, B12 supports the methylation cycle , a chemical pathway involved in energy metabolism and detoxification

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Also, in most people, methyl and adenosyl B12 can inter-convert easily, so the exclusive supplementation of methyl B12 is enough in most cases

B vitamins are enzyme cofactors that play an important role in energy metabolism

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