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Briefly, female BALB/c mice (6 weeks old) were fasted for 12 h, and a small amount of sterile medical-grade lubricant was applied to the anal region prior to rectal administration to facilitate insertion and minimize mechanical irritation

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422.7: Necroptosis plays a role in acute kidney injury (AKI) and the progression to renal fibrosis following ischemia reperfusion injury (IRI)