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It is excreted renally, largely unchanged, with a renal clearance that mirrors creatinine clearance [2]

One reason for this is that fatty acid oxidation is the most efficient way to convert ADP to ATP, the direct source of energy used throughout the body

More specifically, they slow down stomach emptying to help the patient feel full for longer

We believe in a sustainable and flexible approach to nutrition, without imposing limitations on your diet

The most common adverse events were gastrointestinal and dose-related: diarrhea (27.4% / 33.5% / 33.6% at 4 / 9 / 12 mg vs 13.2% on placebo), nausea (13.7% / 20.8% / 28.0% vs 8.0%) and constipation (14.0% / 16.2% / 16.8% vs 9.4%)

Importantly, interindividual variability, including gender differences, hormonal patterns, BC, and microbiota profile, should guide dietary and pharmacological choices