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While research suggests it is safe and well-tolerated in short-term studies when administered in carefully controlled pulses, its unapproved status means: Long-Term Effects are Unknown: The full impact of chronic use on cardiovascular health, glucose regulation, or promotion of latent malignancies is not fully established via large-scale human trials

Kumar et al

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The abdomen tends to produce milder reactions than the thigh for most users, likely because abdominal subcutaneous fat provides a more consistent depot environment with fewer blood vessels

Cost per session: IV treatments carry a higher per-session cost

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