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2 Table 2 Clinical Manifestations of Vitamin B12 Deficiency Maternal vitamin B 12 deficiency during pregnancy or while breastfeeding may lead to neural tube defects, developmental delay, failure to thrive, hypotonia, ataxia, and anemia

Implications for clinical therapy Although, overall, both insulin sensitivity and beta-cell secretion are expected to improve with lowered glucose, HOMA-IR measurements over 8 weeks cannot be used to evaluate the effectiveness of treatment for an individual

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Months 03 Retatrutide Alone, Titration Phase Community-reported staged sequencing keeps cagrilintide off until retatrutide is stable at 2 mg/week

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