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Do not vigorously aspirate in immunization-style injections, but ensure not in a blood vessel (striking a vein is unlikely in recommended sites)

Rotate sites systematically (abdomen, thighs, upper arms) to avoid lipohypertrophy [8]

Stop immediately if severe symptoms occur, such as breathing difficulty, sudden chest pain, severe rash, jaundice, or syncope, and seek emergency care

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This is one reason people sometimes stop losing weight without changing anything, degraded medication delivering less drug than expected