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Those following a vegan or strict plant-based diet are more likely to suffer from vitamin B12 deficiency.
The local effect theory suggests oral administration may actually work better than injection for these purposes
The key difference is dosing range
Freezing at minus 20 degrees Celsius reduces reaction rates substantially (Arrhenius kinetics: roughly a 2- to 3-fold rate reduction per 10 degrees Celsius drop)
B12 injections can help you go from restless nights to getting a good night sleep
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