Dietary adjustmentsincreasing water, fiber, and physical activitytypically manage constipation effectively without stopping the medication
A higher-dose version of semaglutide, called Wegovy, is FDA-approved specifically for long-term weight management in people with obesity and certain health conditions
These gastrointestinal side effects can lead to dehydration, which may compromise kidney function if ibuprofen is used concurrently
For semaglutide-related symptoms, the approach in clinical practice is typically lower: 5-10 mg before the 1-2 meals most associated with symptoms, rather than four-times-daily dosing
de Lucas MD, Bueno BA, Sierra JO
Some people have mild side effects that come and go, especially when their doctor increases their dose