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Acts as an estrogen receptor antagonist in the hypothalamus, leading to increased GnRH, LH, and FSH secretion endogenous testosterone production and spermatogenesis
But that wasn't nearly enough to alleviate the excessive inflammation and pain in her joints during flare-ups, which could last as long as four months
Pathways leading to GLP-1RA induced natriuresis are unclear, with inhibition of the sodium hydrogen exchanger-3 (NHE3) antiporter in the proximal tubule being one possibility 39 - 41
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