Intravenous B12 Administration For those with severe vitamin B12 deficiency, getting B12 through an IV is a quick and effective way to treat it
Although most people are naturally supplied with the correct amount of B12, using a little extra for an energy jolt has no proven downsides, says Elisa Zied, author of Feed Your Family Right
A practitioner asking should I offer MIC? in 2026 is implicitly asking why would I, when I can prescribe a GLP-1? The honest answers are narrower than the marketing, but they are real: Patients who cannot or will not take a GLP-1
in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )
Semaglutide, Tirzepatide, and Retatrutide all fall into this category, though each generation adds more receptor targets
Another test is often done around the eight-week mark to confirm that the treatment has successfully corrected the deficiency