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Compared to other GLP-1 agonists, semaglutide has been shown to be more effective in promoting weight loss, which may be related to its stronger impact on dopamine regulation

Large randomized controlled trials (STEP 1, STEP 2, STEP 3) demonstrated that semaglutide at 2.4 mg weekly produces average weight loss of 1517% of baseline body weight over 68 weeks, with sustained metabolic benefits including improved blood glucose and cardiovascular risk markers

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And that folded in some of the older GLP-1 drugs, like liraglutide, that dont work as well

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