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Oral semaglutide 14 mg daily did not separate from placebo on the CDRSum of Boxes (primary endpoint) or secondary cognitive/functional measures over two years
It spills over to MC3R and MC4R, triggering off-target effects
And Lemme isnt alone in the capsule supplement area
Ongoing clinical and mechanistic studies are expected to expand use of GLP-1 receptor agonists, glucose-dependent insulinotropic polypeptide agonists and other metabolic hormones for the treatment of chronic kidney disease
Buzzword inflation: GLP-1 is doing more for the marketing than the mechanism
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