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By improving factors like blood pressure, cholesterol levels and inflammation markers, semaglutide may help reduce the risk of heart disease a common concern for those struggling with obesity
KWONG: GLP-1s
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The stomach and brain are so connected that intestinal issues can lead to stress, anxiety and depression it's what's known as the "gut-brain connection." "Chronic abdominal pain and unpredictable digestive symptoms such as nausea, diarrhea, fullness or constipation can take a significant toll on your mood and energy levels," Laurie A
Several factors can increase the risk of developing prediabetes, including: Having a body weight classified as overweight or obese Physical inactivity Poor diet Family history of diabetes Being over age 45 Having polycystic ovary syndrome (PCOS) or a history of gestational diabetes Typical treatments for prediabetes focus on lifestyle changes
This amplifies gut-to-brain signaling and increases the brains sensitivity to gastrointestinal sensations ( The bloodbrain barrier around the area postrema, is more porous thus allowing it to act as a chemosensory trigger zone for nausea and vomiting ( Unfortunately, beyond the specific GLP-1 pathways, multi-agonist therapies do not bypass the gastrointestinal adverse events despite broader receptor targeting
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