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However, clinical outcomes are complicated by behavioral factors, including lower adherence rates reported among women, which may obscure the true extent of sex-related efficacy differences [52]

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These adverse events have contributed to the discontinuation of several PDE10A candidates in clinical development (Grauer et al., 2009

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Angew Chem Int Ed 61:16

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Slows gastric emptying, making you feel fuller longer

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