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Secondly, GLP-1 and its analogs protect BBB integrity
The preclinical evidence base for each component is substantial
Cardinali (88887.470274/201900) and Yandara A
This is all done in the service of slowing his rate of ageing until, he hopes, one year of chronological time can pass while his biological age stays the same
The GLP-1 component helps reduce appetite and cravings, while the GIP component is thought to improve how the body breaks down sugar and fat
This is consistent with evidence that perceived stress and body-image disturbance remain central determinants of mood and adjustment in individuals with obesity, including after substantial weight change [72, 73]
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