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Incretin-based therapies, specifically agonists of glucagon-like peptide-1 receptors (GLP-1 RAs) and glucose-dependent insulinotropic polypeptide (GIP) receptors, have demonstrated benefits for regulating appetite, improving glucose homeostasis, and reducing cardiovascular risk (2, 3)
semaglutide up to 1.0 mg qw, n =50
Participants with autoimmune disease, psychiatric disorder, infected ulcer, osteomyelitis, ischemia, and/or contraindications to treatment methods were excluded
Hum Exp Toxicol 41:09603271221111333 Cao Y, Xu Z, Chen Y, Jiang S, Li H, Luo Y (2016) Effects of Dioscorea nipponica on the expression of Th17/Treg cytokines in patients with Hashimoto thyroiditis
Side effects typically become less bothersome or resolve entirely
Gastrointestinal side effects affect up to 40% of people beginning GLP-1 agonist therapy, with diarrhea ranking among the most frequently reported
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