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Weeks 14: 2.5 mg weekly (starter dose) Weeks 58: 5 mg weekly Weeks 912: 7.5 mg weekly Weeks 1316: 10 mg weekly Weeks 1720: 12.5 mg weekly Maintenance: up to 15 mg weekly Some people stay at lower doses for longer if they feel comfortable and still see results

I dati arrivano dallo studio ESSENCE (Sanyal AJ et al., NEJM 2025): a 72 settimane, il 62,9% dei pazienti in semaglutide ha ottenuto risoluzione della MASH senza peggioramento della fibrosi (vs 34,3% del placebo)

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& Pollock, C

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Baicalin alleviates oxidative stress and inflammation in diabetic nephropathy via Nrf2 and MAPK signaling pathway