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Patients should reduce or avoid fried foods, processed foods, refined carbs, and sugary snacks
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PRR, proportional reporting ratio
ibuprofen absorption timing is unpredictable Preferred OTC alternative / acetaminophen 325-650 mg per dose, max 3,000 mg/day for most adults Alcohol safety / moderate intake is not prohibited but worsens GI side effects and blood sugar variability Birth control risk window / first 4-8 weeks of semaglutide, vomiting can impair oral contraceptive absorption Pregnancy / semaglutide must be stopped at least 2 months before a planned conception attempt Time to meaningful weight loss / most patients see 5% body-weight reduction by weeks 12-16 at maintenance dose SELECT trial finding / semaglutide 2.4 mg cut major adverse cardiovascular events by 20% in non-diabetic adults with obesity STEP-1 weight loss / 14.9% mean body weight reduction at 68 weeks vs
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Patients and prescribers should consult the most current SmPC once available, alongside relevant NICE guidance, before initiating retatrutide alongside any existing medication regimen
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